Application

Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.

Research CategoryStem Cell Research

Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.

Research Sub CategoryCell Cycle, DNA Replication & Repair

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.

Immunogen

KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.

Linkage

Replaces: MABD186

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Purified by Ion-Exchange Chromatography

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Format: Purified

Quality

Evaluated by Western Blotting in L6 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~40 kDa observed